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This is an accepted version of this page This is the latest accepted revision, reviewed on 13 September 2024. Group of endocrine diseases characterized by high blood sugar levels This article is about the common insulin disorder. For the urine hyper-production disorder, see Diabetes insipidus. For other uses, see Diabetes (disambiguation). Medical condition Diabetes mellitus Universal blue ...
Diabetes was one of the first diseases ever described, dating back to an Egyptian manuscript from c. 1500 BCE. [21] Type 1 and type 2 diabetes were identified as separate conditions in 400–500 CE with type 1 associated with youth and type 2 with being overweight. [22] The importance of insulin in the disease was determined in the 1920s. [23]
Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. [ 5 ] Insulin is a hormone required for the cells to use blood sugar for energy and it helps regulate glucose levels in the bloodstream. [ 6 ]
Epidemiology of diabetes. Prevalence (per 1,000 inhabitants) of diabetes worldwide in 2000 - world average was 2.8%. Globally, an estimated 537 million adults are living with diabetes, according to 2019 data from the International Diabetes Federation. [1] Diabetes was the 9th-leading cause of mortality globally in 2020, attributing to over 2 ...
Endocrinology. Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults (LADA), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), [3][4] and is sometimes referred to as type 1.5 diabetes. [5] It is an autoimmune form of diabetes, similar to T1D, but ...
Diabetic retinopathy (also known as diabetic eye disease), is a medical condition in which damage occurs to the retina due to diabetes. It is a leading cause of blindness in developed countries. Diabetic retinopathy affects up to 80 percent of those who have had both type 1 and type 2 diabetes for 20 years or more.
SGLT2 inhibitor. SGLT2 inhibitors (also called gliflozins or flozins) are a class of medications that inhibit sodium-glucose transport proteins in the nephron (the functional units of the kidney), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa. The foremost metabolic effect of this is to inhibit reabsorption of ...
Features of poisoning differ depending on whether the agent is an organic compound (one that contains carbon), or an inorganic one. [26] Organic lead poisoning is now very rare, because countries across the world have phased out the use of organic lead compounds as gasoline additives , but such compounds are still used in industrial settings ...
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