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These metabolites show approximately 20% of the inhibitory activity of finasteride on 5α-reductase. [5] Hence, the metabolites of finasteride are not particularly active. [ 5 ] The drug has a terminal half-life of 5 to 6 hours in adult men (18–60 years of age) and a terminal half-life of 8 hours or more in elderly men (more than 70 years of ...
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